From LAX/Long Beach Airport
- Take the 405 Freeway South
- Take exit 1C for Irvine Center Drive
- In 0.3 miles, turn Left onto Irvine Center Drive
- In 0.6 miles, turn Right onto Alton Parkway
- In 0.1 mile, turn right onto Gateway
- In 275 feet, turn Left
- 400 Spectrum Center Drive will be on the right; the parking structure will be on the left.
From downtown LA
- Take the 5 Freeway South toward Santa Ana and San Diego
- Take exit 94 toward Spectrum Center Drive
- Keep Left at the offramp; follow signs for Spectrum Center Drive/Enterprise Drive
- In 0.1 mile, turn right onto Gateway
- In 436 feet, turn Right
- 400 Spectrum Center Drive will be on the right; the parking structure will be on the left.
From John Wayne Airport (SNA)
- Take the 405 Freeway South; follow signs for Interstate 405 South/San Diego
- Take exit 1C for Irvine Center Drive
- In 0.3 miles, turn Left onto Irvine Center Drive
- In 0.6 miles, turn Right onto Alton Parkway
- In 0.1 mile, turn right onto Gateway
- In 275 feet, turn Left
- 400 Spectrum Center Drive will be on the right; the parking structure will be on the left.
From San Diego area
- Take the 5 freeway North toward Santa Ana
- Take exit 94B for Alton Parkway
- In 0.2 miles, turn Left onto Alton Parkway
- In 0.3 miles, turn Left onto Gateway
- In 360 feet, turn Left
- 400 Spectrum Center Drive will be on the right; the parking structure will be on the left.