Mark DeLuca is a patent agent specializing in organic chemistry and chemical processes. He has experience with preparing, filing and prosecuting US and foreign patent applications in the areas of small molecule pharmaceuticals, drug formulation, biotechnology, polymer chemistry and medical devices. He conducts IP diligence including preparing freedom-to-operate, patentability, infringement and validity analyses. He also provides litigation analysis and support including assisting attorneys at depositions and drafting pleadings.

His Ph.D. research was involved with the synthesis of complex natural products. During this research Dr. DeLuca was involved in the completion of the total synthesis of the natural products: koumine, strychnine, and UK-1. After completion of his Ph.D., Dr. DeLuca worked as a Research Associate in the Department of Medicinal Chemistry at the University of Texas at Austin. In this position, Dr. DeLuca’s research involved the synthesis and analysis of novel heterocyclic compounds for use in the treatment of cancer and osteoporosis.


  • Co-Author, U.S. Patent No. 6,720,344 – “Methods and compositions for stimulating osteoblast proliferation or treating malignant cell proliferation and methods for selecting osteoblast proliferation stimulants”
  • Co-Author, “New strategy for the synthesis of taxane diterpenes: formation of the BC-rings of taxol via a [5+2]-pyrylium ylide-aldehyde cyclization, ring expansion strategy’, Tetrahedron Lett, 1995, 36, 5327
  • Co-Author, “Synthesis of strychnine and the Wieland-Gumlich aldehyde”, J. Am. Chem. Soc., 1993, 115, 8116
  • Co-Author, “Studies on the synthesis of ginkgolides.  Rapid construction of the spiro[4.4]nonane A and B rings”,  J. Chem. Soc. Perkin I, 1991, 2661
  • Co-Author, “Total Synthesis of (+)-koumine, (+)-taberpsychine, and (+)-koumidine”, J. Am. Chem. Soc., 1990, 111, 786
  • Co-Author, “Cross-conjugated and pseudo-cross-conjugated mesomeric betaines. 2. Structure and Reactivity”, J. Org. Chem., 1988, 53, 2898